PharmacologyQuestion 79 of 100

Which route of administration generally produces the fastest onset of drug action?

a.Oral tablets swallowed with water
b.Transdermal patch applied to the chest
c.Rectal suppository
d.Intravenous injection

Explanation

Intravenous administration places the drug directly into the bloodstream, so it acts fastest with essentially complete bioavailability. Oral tablets must dissolve and pass through absorption and liver metabolism before acting. Transdermal patches are designed for slow, steady release over hours or days, and rectal absorption is variable and slower than intravenous.

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