Anatomy & SciencesQuestion 298 of 484

A client develops itchy, blistering hand eczema only after she begins wearing nitrile gloves with a specific accelerator chemical. This delayed reaction, mediated by T-cells, is best classified as:

a.Bacterial folliculitis
b.Acute anaphylaxis (Type I hypersensitivity)
c.Allergic contact dermatitis (Type IV hypersensitivity)
d.Irritant contact dermatitis from soap dryness

Explanation

Allergic contact dermatitis is a T-cell-mediated, delayed (Type IV) reaction to a specific allergen, often appearing 24-72 hours after exposure. Irritant contact dermatitis is not immune-mediated and usually appears quickly with strong irritants.

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