Anatomy & SciencesQuestion 298 of 484
A client develops itchy, blistering hand eczema only after she begins wearing nitrile gloves with a specific accelerator chemical. This delayed reaction, mediated by T-cells, is best classified as:
a.Allergic contact dermatitis (Type IV hypersensitivity)
b.Irritant contact dermatitis from soap dryness
c.Acute anaphylaxis (Type I hypersensitivity)
d.Bacterial folliculitis
Explanation
Allergic contact dermatitis is a T-cell-mediated, delayed (Type IV) reaction to a specific allergen, often appearing 24-72 hours after exposure. Irritant contact dermatitis is not immune-mediated and usually appears quickly with strong irritants.
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