Federal RequirementsQuestion 43 of 100

What is DEA Form 222 (or its electronic CSOS equivalent) used for?

a.Ordering or transferring Schedule II controlled substances between DEA registrants
b.Reporting a theft of controlled substances to the DEA
c.Documenting the destruction of expired controlled substances
d.Registering a new pharmacy with the DEA

Explanation

DEA Form 222, or an electronic order placed through the Controlled Substance Ordering System (CSOS), is required for every purchase or transfer of a Schedule II substance between registrants. Schedules III through V may be ordered on an ordinary invoice and do not require Form 222, although the invoice must still be retained. Theft reporting uses Form 106, destruction uses Form 41, and initial pharmacy registration uses Form 224.

Law Reference: 21 CFR 1305 (DEA Form 222 / CSOS)

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