Specimen HandlingQuestion 65 of 100

A chemistry specimen arrives visibly hemolyzed. Which result is most likely to be falsely elevated?

a.Sodium
b.Potassium
c.Albumin
d.Chloride

Explanation

Potassium is far more concentrated inside red cells than in plasma, so cell rupture releases it and drives the measured value up sharply. LDH, AST and magnesium rise for the same reason. Sodium and chloride are higher outside the cells, and albumin is a plasma protein unaffected by red cell lysis.

Law Reference: CLSI GP44

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