MedicationsQuestion 27 of 100
A patient taking lisinopril reports a persistent dry, tickling cough that started a few weeks after beginning therapy. What is the most likely explanation?
a.Dry cough is a recognized ACE inhibitor effect related to bradykinin accumulation
b.The cough indicates an allergic reaction requiring epinephrine
c.The cough is a sign that the dose is too low
d.Lisinopril does not cause cough, so the symptom is unrelated
Explanation
ACE inhibitors block breakdown of bradykinin in the respiratory tract, and the resulting dry, nonproductive cough is a well-known reason patients are switched to an ARB such as losartan. It is not an anaphylactic reaction, and the cough is dose-independent rather than a sign of underdosing.
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