MedicationsQuestion 30 of 100
A patient stabilized on warfarin asks whether it is acceptable to take ibuprofen for back pain. What is the appropriate response?
a.Ibuprofen has no interaction with warfarin and may be taken freely
b.Ibuprofen raises bleeding risk with warfarin; the patient should check with the prescriber first
c.Ibuprofen decreases warfarin's effect, so the warfarin dose must be doubled
d.Ibuprofen may be taken only if the warfarin dose is skipped that day
Explanation
NSAIDs such as ibuprofen irritate the gastrointestinal lining and inhibit platelet function, which adds to warfarin's anticoagulant effect and increases bleeding risk, so the prescriber should be consulted and acetaminophen is often preferred. The interaction increases rather than decreases bleeding risk, and patients should never adjust or skip warfarin doses on their own.
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