MedicationsQuestion 29 of 100

A patient is starting a course of metronidazole. Which counseling point is most important?

a.Avoid alcohol during therapy and for several days after the last dose
b.Take each dose on a completely empty stomach
c.Expect the urine to turn bright blue
d.Double the next dose if one is missed

Explanation

Metronidazole combined with alcohol can produce a disulfiram-like reaction with flushing, nausea, vomiting, and palpitations, so alcohol is avoided during and shortly after therapy. The drug may be taken with food to reduce stomach upset, it can darken urine rather than turn it blue, and doses are never doubled after a missed dose.

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