ACLS — Advanced Cardiovascular Life Support Practice Test

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A full bank of original ACLS — Advanced Cardiovascular Life Support practice questions across the official content areas, weighted like the real exam, with explanations. Free, no signup.

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A multiple-choice exam. Practice by topic here, then take the full timed mock exam to gauge readiness.

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Sample practice questions

A few real questions from this free bank, with full explanations. Use the practice tool above for the whole set.

  1. 1. High-Quality BLS & AED

    What is the recommended chest compression rate for high-quality CPR in an adult?

    • a.60 to 80 compressions per minute
    • b.80 to 100 compressions per minute
    • c.100 to 120 compressions per minute
    • d.120 to 140 compressions per minute

    Answer: c

    Explanation: Current AHA guidelines call for a compression rate of 100 to 120 per minute. Rates slower than 100 reduce coronary and cerebral perfusion, while rates faster than 120 shorten the recoil/filling phase and reduce the depth actually achieved, so the diastolic filling of the heart suffers. Staying inside the 100-120 window balances forward blood flow with adequate ventricular filling.

  2. 2. Rhythm Recognition (ECG)

    A stable patient has a regular narrow-complex tachycardia at 180 bpm; vagal maneuvers have not worked. The next appropriate step is:

    • a.Defibrillate the patient
    • b.Give adenosine 6 mg by rapid IV push
    • c.Give atropine 1 mg IV
    • d.Give epinephrine 1 mg IV push

    Answer: b

    Explanation: A regular narrow-complex tachycardia that persists after vagal maneuvers in a stable patient is treated with adenosine 6 mg rapid IV push (then 12 mg if needed). This most likely represents a re-entrant SVT, and adenosine's transient AV nodal block can break the circuit. Defibrillation, atropine, and arrest-dose epinephrine are all inappropriate for a stable, perfusing SVT.

  3. 3. High-Quality BLS & AED

    During CPR the ETCO2 is 9 mm Hg. What adjustment is most likely to help?

    • a.Give sodium bicarbonate
    • b.Increase ventilations to 30 per minute
    • c.Stop CPR for a rhythm check
    • d.Improve compression depth and rate

    Answer: d

    Explanation: ETCO2 reflects cardiac output during CPR and rises with better compression depth; the Guidelines suggest targeting at least 10 and ideally 20 mm Hg. Faster ventilation risks harm and bicarbonate is not routine.

  4. 4. Airway Management & Ventilation

    What basic airway strategy does resuscitation usually start with?

    • a.Bag-mask ventilation
    • b.Supraglottic airway only
    • c.Surgical airway
    • d.Intubation before CPR

    Answer: a

    Explanation: Airway management during cardiac arrest usually begins with bag-mask ventilation, with an advanced airway added according to skill and setting.

  5. 5. ACLS Pharmacology

    For VF that persists after defibrillation, which antiarrhythmics improved survival to hospital admission in a large trial?

    • a.Amiodarone and lidocaine
    • b.Diltiazem and verapamil
    • c.Magnesium and calcium
    • d.Adenosine and atropine

    Answer: a

    Explanation: A large placebo-controlled prehospital trial found amiodarone and lidocaine each improved survival to admission, without a difference in survival to discharge.

  6. 6. ACLS Pharmacology

    Which drug route for epinephrine did the 2025 Guidelines remove?

    • a.Central venous
    • b.Through the endotracheal tube
    • c.Intraosseous
    • d.Intravenous

    Answer: b

    Explanation: Administering intra-arrest medications via an endotracheal tube was removed because it produces low blood concentrations and unpredictable effects.

  7. 7. Rhythm Recognition (ECG)

    Why does a narrow-complex tachycardia in a septic patient need careful interpretation?

    • a.It may be a response
    • b.It must be shocked at once
    • c.It cannot occur with fever
    • d.It is always VT in disguise

    Answer: a

    Explanation: There must be a reasonable expectation that a narrow-complex tachycardia is causing instability rather than being a manifestation of another illness such as sepsis.

  8. 8. Cardiac Arrest Algorithms

    Which intervention for a suspected massive pulmonary embolism arrest do the Guidelines discuss?

    • a.Atropine
    • b.Systemic fibrinolysis
    • c.Synchronized cardioversion
    • d.Adenosine

    Answer: b

    Explanation: Treatments for arrest from PE include systemic and catheter-guided fibrinolysis, surgical and mechanical embolectomy, and ECMO.

  9. 9. Bradycardia & Tachycardia

    Why is verapamil dangerous for a wide-complex tachycardia of ventricular origin?

    • a.It is too slow to work
    • b.It causes torsades only in children
    • c.It speeds the ventricular rate to 300
    • d.It can cause shock and arrest

    Answer: d

    Explanation: Verapamil will not terminate a WCT of ventricular origin and may cause profound hypotension leading to shock and cardiac arrest.

  10. 10. ACS, Stroke & Post-Arrest Care

    When is supplemental oxygen indicated in suspected ACS?

    • a.For every patient
    • b.SpO2 below 90%
    • c.Never
    • d.SpO2 below 99%

    Answer: b

    Explanation: Oxygen may benefit patients with saturations below 90%, while routine oxygen shows no benefit at saturations of 90% or more.

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