PANCE (Physician Assistant National Certifying Exam) exam topics — the 15 content areas by weight
The PANCE (Physician Assistant National Certifying Exam) exam is built from 15 weighted content areas. Focus your time where the weight is. Each area below links to a free study chapter and practice questions. These weights are how PrepPass has organized the material, not a figure published by the exam authority.
Cardiovascular System
11%Dermatologic System
4%Endocrine System
6%Eyes, Ears, Nose, and Throat
6%Gastrointestinal System/Nutrition
8%Genitourinary System
4%Hematologic System
5%Infectious Diseases
7%Musculoskeletal System
8%Neurologic System
7%Psychiatry/Behavioral Science
7%Pulmonary System
9%Renal System
5%Reproductive System
7%Professional Practice
6%Ready to test yourself?
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Content-area weights are PrepPass’s own organization of the material. Where PANCE (Physician Assistant National Certifying Exam) publishes an official outline, check it directly. Confirm current details with NCCPA. Study aid, not a substitute for the official material. Last updated: August 2026.